Department of Ophthalmology Written by Kara Mason | December 06, 2023 A partnership between ophthalmology researchers at the University of Colorado School of Medicine and Johns Hopkins University expands the understanding of how oxidative stress contributes to the development of choroidal neovascularization (CNV) in patients with age-related macular degeneration (AMD). To study the roles oxidative stress, a condition in which the body lacks antioxidants, and hypoxia play in the progression of AMD, Johns Hopkins University researchers turned to CellSight , the ocular stem cell and regeneration research program in the CU Department of Ophthalmology, for tools that allow researchers to explore specific conditions relevant to AMD. Using human-induced pluripotent stem cells, a type of stem cells that are generated or induced-from cells obtained from an adult person's skin or blood, CellSight investigators can recreate human retinal tissue in the lab. “We generate retinal orga