UNDERSTANDING CORONARY HEART DISEASE (CHD) According to current estimates, 64.4 million Americans have one or more types of cardiovascular disease. Within cardiovascular diseases, coronary heart disease (CHD) is the single largest killer of Americans. CHD caused 502,189 deaths in the US in 2001 – about 1 in every 5. The American Heart Association estimates that 13.2 million Americans have CHD. In fact, up to half of all sudden, out-of-hospital cardiac deaths occur in people with no prior diagnosis of heart disease, and over two-thirds of heart attach sufferers have blockages in their arteries considered to be clinically “insignificant” in terms of plaque burden and percent stenosis. Until recently, it was widely held that most heart attacks were caused by a gradual build-up of atherosclerotic plaque within the arteries of the heart (“hardening of the arteries”), impedes blood flow, and eventually results in blocked blood vessels that can cause acute ischemic events such as...